5yza: Difference between revisions

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OCA

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-'''Unreleased structure'''
-The entry 5yza is ON HOLD
+==Crystal Structure of Human CRMP-2 with S522D mutation==
+<StructureSection load='5yza' size='340' side='right'caption='[[5yza]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5yza]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YZA FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5yza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yza OCA], [https://pdbe.org/5yza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5yza RCSB], [https://www.ebi.ac.uk/pdbsum/5yza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5yza ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DPYL2_HUMAN DPYL2_HUMAN] Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton (By similarity). Plays a role in neuron projection morphogenesis.<ref>PMID:11477421</ref> <ref>PMID:15466863</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Aoki M]]
+[[Category: Imasaki T]]
+[[Category: Nitta E]]
+[[Category: Nitta R]]
+[[Category: Sakai N]]
+[[Category: Shirouzu M]]
+[[Category: Sumi T]]