5xrk: Difference between revisions

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New page: '''Unreleased structure''' The entry 5xrk is ON HOLD until Paper Publication Authors: Su, J. Description: Galectin-10/Charcot-Leyden crystal protein variant C57A crystal structure [[Ca...
 
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'''Unreleased structure'''


The entry 5xrk is ON HOLD  until Paper Publication
==Galectin-10/Charcot-Leyden crystal protein variant C57A crystal structure==
<StructureSection load='5xrk' size='340' side='right'caption='[[5xrk]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5xrk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XRK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XRK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xrk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xrk OCA], [https://pdbe.org/5xrk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xrk RCSB], [https://www.ebi.ac.uk/pdbsum/5xrk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xrk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LEG10_HUMAN LEG10_HUMAN] Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg).<ref>PMID:17502455</ref>


Authors: Su, J.
==See Also==
 
*[[Galectin 3D structures|Galectin 3D structures]]
Description: Galectin-10/Charcot-Leyden crystal protein variant C57A crystal structure
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Su, J]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Su J]]

Latest revision as of 13:20, 27 March 2024

Galectin-10/Charcot-Leyden crystal protein variant C57A crystal structureGalectin-10/Charcot-Leyden crystal protein variant C57A crystal structure

Structural highlights

5xrk is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.7Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LEG10_HUMAN Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg).[1]

See Also

References

  1. ↑ Kubach J, Lutter P, Bopp T, Stoll S, Becker C, Huter E, Richter C, Weingarten P, Warger T, Knop J, Mullner S, Wijdenes J, Schild H, Schmitt E, Jonuleit H. Human CD4+CD25+ regulatory T cells: proteome analysis identifies galectin-10 as a novel marker essential for their anergy and suppressive function. Blood. 2007 Sep 1;110(5):1550-8. doi: 10.1182/blood-2007-01-069229. Epub 2007 May, 14. PMID:17502455 doi:http://dx.doi.org/10.1182/blood-2007-01-069229

5xrk, resolution 1.70Å

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