5x0x: Difference between revisions
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==Complex of Snf2-Nucleosome complex with Snf2 bound to position +6 of the nucleosome== | |||
<SX load='5x0x' size='340' side='right' viewer='molstar' caption='[[5x0x]], [[Resolution|resolution]] 3.97Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5x0x]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C], [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X0X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5X0X FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.97Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5x0x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x0x OCA], [https://pdbe.org/5x0x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5x0x RCSB], [https://www.ebi.ac.uk/pdbsum/5x0x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5x0x ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/H32_XENLA H32_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | |||
==See Also== | |||
*[[Helicase 3D structures|Helicase 3D structures]] | |||
*[[Histone 3D structures|Histone 3D structures]] | |||
[[Category: | __TOC__ | ||
</SX> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae S288C]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Xenopus laevis]] | |||
[[Category: Chen Z]] | |||
[[Category: Li M]] | |||
[[Category: Li X]] | |||
[[Category: Liu X]] | |||
[[Category: Xia X]] |