1e4o: Difference between revisions

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[[Image:1e4o.png|left|200px]]


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==Phosphorylase recognition and phosphorolysis of its oligosaccharide substrate: answers to a long outstanding question==
The line below this paragraph, containing "STRUCTURE_1e4o", creates the "Structure Box" on the page.
<StructureSection load='1e4o' size='340' side='right'caption='[[1e4o]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1e4o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E4O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E4O FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
{{STRUCTURE_1e4o|  PDB=1e4o  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e4o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e4o OCA], [https://pdbe.org/1e4o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e4o RCSB], [https://www.ebi.ac.uk/pdbsum/1e4o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e4o ProSAT]</span></td></tr>
 
</table>
===PHOSPHORYLASE RECOGNITION AND PHOSPHOROLYSIS OF ITS OLIGOSACCHARIDE SUBSTRATE: ANSWERS TO A LONG OUTSTANDING QUESTION===
== Function ==
 
[https://www.uniprot.org/uniprot/PHSM_ECOLI PHSM_ECOLI] Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_10469642}}, adds the Publication Abstract to the page
Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e4/1e4o_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_10469642}}
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
[[1e4o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E4O OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e4o ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
<ref group="xtra">PMID:010469642</ref><references group="xtra"/>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Phosphorylase]]
[[Category: Large Structures]]
[[Category: Cottaz, S.]]
[[Category: Cottaz S]]
[[Category: Driguez, H.]]
[[Category: Driguez H]]
[[Category: Geremia, S.]]
[[Category: Geremia S]]
[[Category: Johnson, L N.]]
[[Category: Johnson LN]]
[[Category: Mccleverty, C.]]
[[Category: McCleverty C]]
[[Category: Watson, K A.]]
[[Category: Watson KA]]
[[Category: Binary and ternary oligosaccharide complex]]
[[Category: Carbohydrate recognition]]
[[Category: Hydrolase]]
[[Category: Maltopentaose]]
[[Category: Phosphorylase]]

Latest revision as of 12:58, 20 March 2024

Phosphorylase recognition and phosphorolysis of its oligosaccharide substrate: answers to a long outstanding questionPhosphorylase recognition and phosphorolysis of its oligosaccharide substrate: answers to a long outstanding question

Structural highlights

1e4o is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.9Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PHSM_ECOLI Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1e4o, resolution 2.90Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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