1dph: Difference between revisions

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-{{Seed}}
-[[Image:1dph.png|left|200px]]
-<!--
+==CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11==
-The line below this paragraph, containing "STRUCTURE_1dph", creates the "Structure Box" on the page.
+<StructureSection load='1dph' size='340' side='right'caption='[[1dph]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1dph]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DPH FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DCE:1,2-DICHLOROETHANE'>DCE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-{{STRUCTURE_1dph|  PDB=1dph  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dph OCA], [https://pdbe.org/1dph PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dph RCSB], [https://www.ebi.ac.uk/pdbsum/1dph PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dph ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/INS_BOVIN INS_BOVIN] Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dp/1dph_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dph ConSurf].
+<div style="clear:both"></div>
-===CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11===
+==See Also==
+*[[Insulin 3D Structures|Insulin 3D Structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_1477273}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 1477273 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_1477273}}
-==About this Structure==
-DPH is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPH OCA].
-==Reference==
-<ref group="xtra">PMID:1477273</ref><references group="xtra"/>
 [[Category: Bos taurus]]
-[[Category: Badger, J.]]
+[[Category: Large Structures]]
-[[Category: Caspar, D L.D.]]
+[[Category: Badger J]]
-[[Category: Gursky, O.]]
+[[Category: Caspar DLD]]
-[[Category: Li, Y.]]
+[[Category: Gursky O]]
-[[Category: Hormone]]
+[[Category: Li Y]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:07:11 2009''