6nn6: Difference between revisions

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-'''Unreleased structure'''
-The entry 6nn6 is ON HOLD
+==Structure of Dot1L-H2BK120ub nucleosome complex==
+<SX load='6nn6' size='340' side='right' viewer='molstar' caption='[[6nn6]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6nn6]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NN6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NN6 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.9&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6nn6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nn6 OCA], [https://pdbe.org/6nn6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6nn6 RCSB], [https://www.ebi.ac.uk/pdbsum/6nn6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6nn6 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/H32_XENLA H32_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
-Authors: Anderson, C.J., Baird, M.R., Hsu, A., Barbour, E.H., Koyama, Y., Borgnia, M.J., McGinty, R.K.
+==See Also==
+*[[Histone 3D structures|Histone 3D structures]]
-Description: Structure of Dot1L-H2BK120ub nucleosome complex
+*[[Histone methyltransferase 3D structures|Histone methyltransferase 3D structures]]
-[[Category: Unreleased Structures]]
+__TOC__
-[[Category: Mcginty, R.K]]
+</SX>
-[[Category: Anderson, C.J]]
+[[Category: Homo sapiens]]
-[[Category: Koyama, Y]]
+[[Category: Large Structures]]
-[[Category: Baird, M.R]]
+[[Category: Synthetic construct]]
-[[Category: Borgnia, M.J]]
+[[Category: Xenopus laevis]]
-[[Category: Barbour, E.H]]
+[[Category: Anderson CJ]]
-[[Category: Hsu, A]]
+[[Category: Baird MR]]
+[[Category: Barbour EH]]
+[[Category: Borgnia MJ]]
+[[Category: Hsu A]]
+[[Category: Koyama Y]]
+[[Category: McGinty RK]]