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==Crystal structure of Spindlin1 bound to compound EML405==
==Crystal structure of Spindlin1 bound to compound EML405==
<StructureSection load='5jsg' size='340' side='right' caption='[[5jsg]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='5jsg' size='340' side='right'caption='[[5jsg]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5jsg]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JSG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JSG FirstGlance]. <br>
<table><tr><td colspan='2'>[[5jsg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JSG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JSG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6P9:[2-(PHENYLAMINO)-1,4-PHENYLENE]BIS({4-[2-(PYRROLIDIN-1-YL)ETHYL]PIPERIDIN-1-YL}METHANONE)'>6P9</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jsj|5jsj]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6P9:[2-(PHENYLAMINO)-1,4-PHENYLENE]BIS({4-[2-(PYRROLIDIN-1-YL)ETHYL]PIPERIDIN-1-YL}METHANONE)'>6P9</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jsg OCA], [http://pdbe.org/5jsg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jsg RCSB], [http://www.ebi.ac.uk/pdbsum/5jsg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jsg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jsg OCA], [https://pdbe.org/5jsg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jsg RCSB], [https://www.ebi.ac.uk/pdbsum/5jsg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jsg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SPIN1_HUMAN SPIN1_HUMAN]] May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity).  
[https://www.uniprot.org/uniprot/SPIN1_HUMAN SPIN1_HUMAN] May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity).
 
==See Also==
*[[Spindlin|Spindlin]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Li, H]]
[[Category: Homo sapiens]]
[[Category: Su, X]]
[[Category: Large Structures]]
[[Category: Beta barrel]]
[[Category: Li H]]
[[Category: Cell cycle]]
[[Category: Su X]]
[[Category: Sh3-like]]

Latest revision as of 12:17, 20 March 2024

Crystal structure of Spindlin1 bound to compound EML405Crystal structure of Spindlin1 bound to compound EML405

Structural highlights

5jsg is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.5Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SPIN1_HUMAN May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity).

See Also

5jsg, resolution 2.50Å

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