5glj: Difference between revisions

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New page: '''Unreleased structure''' The entry 5glj is ON HOLD Authors: Lee, S.O., Ku, B., Chi, S.W. Description: Crystal Structure of PDZ1 Domain of Human Protein Tyrosine Phosphatase PTP-Bas [...
 
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'''Unreleased structure'''


The entry 5glj is ON HOLD
==Crystal Structure of PDZ1 Domain of Human Protein Tyrosine Phosphatase PTP-Bas==
<StructureSection load='5glj' size='340' side='right'caption='[[5glj]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5glj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GLJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GLJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5glj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5glj OCA], [https://pdbe.org/5glj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5glj RCSB], [https://www.ebi.ac.uk/pdbsum/5glj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5glj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PTN13_HUMAN PTN13_HUMAN] Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.<ref>PMID:15611135</ref>


Authors: Lee, S.O., Ku, B., Chi, S.W.
==See Also==
 
*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
Description: Crystal Structure of PDZ1 Domain of Human Protein Tyrosine Phosphatase PTP-Bas
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Lee, S.O]]
__TOC__
[[Category: Ku, B]]
</StructureSection>
[[Category: Chi, S.W]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Chi SW]]
[[Category: Ku B]]
[[Category: Lee SO]]

Latest revision as of 12:12, 20 March 2024

Crystal Structure of PDZ1 Domain of Human Protein Tyrosine Phosphatase PTP-BasCrystal Structure of PDZ1 Domain of Human Protein Tyrosine Phosphatase PTP-Bas

Structural highlights

5glj is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.6Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PTN13_HUMAN Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.[1]

See Also

References

  1. ↑ Villa F, Deak M, Bloomberg GB, Alessi DR, van Aalten DM. Crystal structure of the PTPL1/FAP-1 human tyrosine phosphatase mutated in colorectal cancer: evidence for a second phosphotyrosine substrate recognition pocket. J Biol Chem. 2005 Mar 4;280(9):8180-7. Epub 2004 Dec 20. PMID:15611135 doi:10.1074/jbc.M412211200

5glj, resolution 1.60Å

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