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The | ==Crystal structure of Marburg virus nucleoprotein core domain== | ||
<StructureSection load='5f5m' size='340' side='right'caption='[[5f5m]], [[Resolution|resolution]] 2.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5f5m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lake_Victoria_marburgvirus_-_Ozolin Lake Victoria marburgvirus - Ozolin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F5M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5F5M FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.902Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5f5m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f5m OCA], [https://pdbe.org/5f5m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5f5m RCSB], [https://www.ebi.ac.uk/pdbsum/5f5m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5f5m ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/NCAP_MABVO NCAP_MABVO] Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication. During replication, encapsidation by NP is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity). | |||
==See Also== | |||
*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Lake Victoria marburgvirus - Ozolin]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Dong SS]] | ||
[[Category: | [[Category: Guo Y]] | ||
[[Category: | [[Category: Li GB]] | ||
[[Category: | [[Category: Liu BC]] | ||
[[Category: | [[Category: Liu X]] | ||
[[Category: Wang WJ]] | |||
[[Category: Wang WM]] | |||
Latest revision as of 12:11, 20 March 2024
Crystal structure of Marburg virus nucleoprotein core domainCrystal structure of Marburg virus nucleoprotein core domain
Structural highlights
FunctionNCAP_MABVO Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication. During replication, encapsidation by NP is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity). See Also |
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