5b4e: Difference between revisions

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-'''Unreleased structure'''
-The entry 5b4e is ON HOLD  until Jun 03 2018
+==Sulfur Transferase TtuA in complex with iron sulfur cluster and ATP derivative==
+<StructureSection load='5b4e' size='340' side='right'caption='[[5b4e]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-Authors: Chen, M., Narai, S., Tanaka, Y., Yao, M.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5b4e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB27 Thermus thermophilus HB27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5B4E FirstGlance]. <br>
-Description: Enzyme Veg136 protein in complex with ligand
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.698&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Chen, M]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5b4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b4e OCA], [https://pdbe.org/5b4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5b4e RCSB], [https://www.ebi.ac.uk/pdbsum/5b4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5b4e ProSAT]</span></td></tr>
-[[Category: Yao, M]]
+</table>
-[[Category: Tanaka, Y]]
+== Function ==
-[[Category: Narai, S]]
+[https://www.uniprot.org/uniprot/TTUA_THET2 TTUA_THET2] Catalyzes the ATP-dependent 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2-thiouridine (m(5)s(2)U or s(2)T) (PubMed:16547008, PubMed:28439027). This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is required for cell growth at high temperatures (PubMed:16547008). TtuA transfers the S atom from the thiocarboxylated C-terminus of TtuB to tRNA (PubMed:28439027).<ref>PMID:16547008</ref> <ref>PMID:28439027</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Thermus thermophilus HB27]]
+[[Category: Chen M]]
+[[Category: Narai S]]
+[[Category: Tanaka Y]]
+[[Category: Yao M]]