5b42: Difference between revisions
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==Crystal structure of the C-terminal endonuclease domain of Aquifex aeolicus MutL.== | |||
<StructureSection load='5b42' size='340' side='right'caption='[[5b42]], [[Resolution|resolution]] 1.35Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5b42]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B42 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5B42 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5b42 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b42 OCA], [https://pdbe.org/5b42 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5b42 RCSB], [https://www.ebi.ac.uk/pdbsum/5b42 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5b42 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MUTL_AQUAE MUTL_AQUAE] This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). | |||
==See Also== | |||
*[[DNA mismatch repair protein 3D structures|DNA mismatch repair protein 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Baba | [[Category: Aquifex aeolicus VF5]] | ||
[[Category: Fukui | [[Category: Large Structures]] | ||
[[Category: | [[Category: Baba S]] | ||
[[Category: | [[Category: Fukui K]] | ||
[[Category: Kumasaka T]] | |||
[[Category: Yano T]] | |||
Latest revision as of 12:07, 20 March 2024
Crystal structure of the C-terminal endonuclease domain of Aquifex aeolicus MutL.Crystal structure of the C-terminal endonuclease domain of Aquifex aeolicus MutL.
Structural highlights
FunctionMUTL_AQUAE This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). See Also |
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