4xwj: Difference between revisions
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==Histidine-containing phosphocarrier protein (HPr) and antisigma factor Rsd complex== | |||
<StructureSection load='4xwj' size='340' side='right'caption='[[4xwj]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4xwj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XWJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XWJ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.095Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xwj OCA], [https://pdbe.org/4xwj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xwj RCSB], [https://www.ebi.ac.uk/pdbsum/4xwj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xwj ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RSD_ECOLI RSD_ECOLI] Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.<ref>PMID:9560209</ref> <ref>PMID:10368152</ref> | |||
==See Also== | |||
*[[Phosphocarrier protein HPr 3D structures|Phosphocarrier protein HPr 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli K-12]] | ||
[[Category: Large Structures]] | |||
[[Category: Ha NC]] | |||
[[Category: Seok YJ]] | |||
[[Category: Um SH]] | |||
Latest revision as of 12:02, 20 March 2024
Histidine-containing phosphocarrier protein (HPr) and antisigma factor Rsd complexHistidine-containing phosphocarrier protein (HPr) and antisigma factor Rsd complex
Structural highlights
FunctionRSD_ECOLI Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.[1] [2] See AlsoReferences
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