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{{STRUCTURE_4mwh|  PDB=4mwh  |  SCENE=  }}
===Crystal structure of scCK2 alpha in complex with ATP===


==Function==
==Crystal structure of scCK2 alpha in complex with ATP==
[[http://www.uniprot.org/uniprot/CSK21_YEAST CSK21_YEAST]] Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. May play a role in cell proliferation. Required for cell viability.  
<StructureSection load='4mwh' size='340' side='right'caption='[[4mwh]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4mwh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MWH FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mwh OCA], [https://pdbe.org/4mwh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mwh RCSB], [https://www.ebi.ac.uk/pdbsum/4mwh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mwh ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CSK21_YEAST CSK21_YEAST] Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. May play a role in cell proliferation. Required for cell viability.


==About this Structure==
==See Also==
[[4mwh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MWH OCA].
*[[Casein kinase 3D structures|Casein kinase 3D structures]]
[[Category: Non-specific serine/threonine protein kinase]]
__TOC__
[[Category: Liu, H.]]
</StructureSection>
[[Category: Protein kinase]]
[[Category: Large Structures]]
[[Category: Protein phosphorylation]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Transferase]]
[[Category: Liu H]]

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