4iy4: Difference between revisions
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==Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4== | ==Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4== | ||
<StructureSection load='4iy4' size='340' side='right' caption='[[4iy4]], [[Resolution|resolution]] 2.90Å' scene=''> | <StructureSection load='4iy4' size='340' side='right'caption='[[4iy4]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4iy4]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4iy4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IY4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IY4 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4iy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iy4 OCA], [https://pdbe.org/4iy4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4iy4 RCSB], [https://www.ebi.ac.uk/pdbsum/4iy4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4iy4 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Disease == | == Disease == | ||
[ | [https://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN] Familial primary hypomagnesemia with normocalcuria and normocalcemia. The disease is caused by mutations affecting the gene represented in this entry. | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN] Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity). | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Accardi | [[Category: Large Structures]] | ||
[[Category: Corral-Rodriguez | [[Category: Accardi A]] | ||
[[Category: Diercks | [[Category: Corral-Rodriguez MA]] | ||
[[Category: Encinar | [[Category: Diercks T]] | ||
[[Category: Ereno-Orbea | [[Category: Encinar JA]] | ||
[[Category: Gomez-Garcia | [[Category: Ereno-Orbea J]] | ||
[[Category: Martinez-Cruz | [[Category: Gomez-Garcia I]] | ||
[[Category: Muller | [[Category: Martinez-Cruz LA]] | ||
[[Category: Oyenarte | [[Category: Muller D]] | ||
[[Category: Spiwok | [[Category: Oyenarte I]] | ||
[[Category: Stuiver | [[Category: Spiwok V]] | ||
[[Category: Terashima | [[Category: Stuiver M]] | ||
[[Category: Terashima H]] | |||
Latest revision as of 11:53, 20 March 2024
Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4
Structural highlights
DiseaseCNNM2_HUMAN Familial primary hypomagnesemia with normocalcuria and normocalcemia. The disease is caused by mutations affecting the gene represented in this entry. FunctionCNNM2_HUMAN Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity). |
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