4fuw: Difference between revisions

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'''Unreleased structure'''


The entry 4fuw is ON HOLD
==Crystal structure of Ego3 mutant==
 
<StructureSection load='4fuw' size='340' side='right'caption='[[4fuw]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
Authors: Zhang, T., Peli-Gulli, M., Yang, H., De Virgilio, C., Ding, J.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4fuw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FUW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FUW FirstGlance]. <br>
Description: Crystal structure of Ego3 mutant
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fuw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fuw OCA], [https://pdbe.org/4fuw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fuw RCSB], [https://www.ebi.ac.uk/pdbsum/4fuw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fuw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SLM4_YEAST SLM4_YEAST] Component of the GSE complex, a GTPase complex required for intracellular sorting of GAP1 out of the endosome. Component of the EGO complex, a complex involved in the regulation of microautophagy.<ref>PMID:15989961</ref> <ref>PMID:16732272</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: De Virgilio C]]
[[Category: Ding J]]
[[Category: Peli-Gulli MP]]
[[Category: Yang H]]
[[Category: Zhang T]]

Latest revision as of 11:50, 20 March 2024

Crystal structure of Ego3 mutantCrystal structure of Ego3 mutant

Structural highlights

4fuw is a 2 chain structure with sequence from Saccharomyces cerevisiae S288C. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.6Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SLM4_YEAST Component of the GSE complex, a GTPase complex required for intracellular sorting of GAP1 out of the endosome. Component of the EGO complex, a complex involved in the regulation of microautophagy.[1] [2]

References

  1. ↑ Dubouloz F, Deloche O, Wanke V, Cameroni E, De Virgilio C. The TOR and EGO protein complexes orchestrate microautophagy in yeast. Mol Cell. 2005 Jul 1;19(1):15-26. PMID:15989961 doi:10.1016/j.molcel.2005.05.020
  2. ↑ Gao M, Kaiser CA. A conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast. Nat Cell Biol. 2006 Jul;8(7):657-67. Epub 2006 May 28. PMID:16732272 doi:ncb1419

4fuw, resolution 2.60Å

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