3x1d: Difference between revisions

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New page: '''Unreleased structure''' The entry 3x1d is ON HOLD Authors: Xinqi Liu, Midwest Center for Structural Genomics (MCSG) Description: Crystal Structure of Atlastin from Drosophila melano...
 
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'''Unreleased structure'''


The entry 3x1d is ON HOLD
==Crystal Structure of Atlastin from Drosophila melanogaster==
<StructureSection load='3x1d' size='340' side='right'caption='[[3x1d]], [[Resolution|resolution]] 2.87&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3x1d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3X1D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3X1D FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.87&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3x1d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3x1d OCA], [https://pdbe.org/3x1d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3x1d RCSB], [https://www.ebi.ac.uk/pdbsum/3x1d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3x1d ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ATLAS_DROME ATLAS_DROME] GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. May also regulate microtubule polymerization and Golgi biogenesis. Required for dopaminergic neurons survival and the growth of muscles and synapses at neuromuscular junctions.<ref>PMID:19341724</ref> <ref>PMID:19633650</ref>


Authors: Xinqi Liu, Midwest Center for Structural Genomics (MCSG)
==See Also==
 
*[[Atlastin 3D structures|Atlastin 3D structures]]
Description: Crystal Structure of Atlastin from Drosophila melanogaster
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Large Structures]]
[[Category: Liu X]]

Latest revision as of 11:48, 20 March 2024

Crystal Structure of Atlastin from Drosophila melanogasterCrystal Structure of Atlastin from Drosophila melanogaster

Structural highlights

3x1d is a 1 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.87Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ATLAS_DROME GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. May also regulate microtubule polymerization and Golgi biogenesis. Required for dopaminergic neurons survival and the growth of muscles and synapses at neuromuscular junctions.[1] [2]

See Also

References

  1. ↑ Lee M, Paik SK, Lee MJ, Kim YJ, Kim S, Nahm M, Oh SJ, Kim HM, Yim J, Lee CJ, Bae YC, Lee S. Drosophila Atlastin regulates the stability of muscle microtubules and is required for synapse development. Dev Biol. 2009 Jun 15;330(2):250-62. doi: 10.1016/j.ydbio.2009.03.019. Epub 2009 , Mar 31. PMID:19341724 doi:http://dx.doi.org/10.1016/j.ydbio.2009.03.019
  2. ↑ Orso G, Pendin D, Liu S, Tosetto J, Moss TJ, Faust JE, Micaroni M, Egorova A, Martinuzzi A, McNew JA, Daga A. Homotypic fusion of ER membranes requires the dynamin-like GTPase atlastin. Nature. 2009 Aug 20;460(7258):978-83. doi: 10.1038/nature08280. Epub 2009 Jul 26. PMID:19633650 doi:http://dx.doi.org/10.1038/nature08280

3x1d, resolution 2.87Å

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