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{{STRUCTURE_3vu9|  PDB=3vu9  |  SCENE=  }}
===Crystal Structure of Psy3-Csm2 complex===


==Function==
==Crystal Structure of Psy3-Csm2 complex==
[[http://www.uniprot.org/uniprot/PSY3_YEAST PSY3_YEAST]] Required for resistance to the DNA-damaging agents methyl methanesulfonate (MMS), cisplatin and oxaliplatin, but not to mitomycin C. Plays a role in protection against mutation accumulation. May be a component of the recombination-repair pathway.<ref>PMID:12149442</ref> <ref>PMID:12482937</ref> <ref>PMID:12972632</ref> <ref>PMID:15173006</ref> <ref>PMID:15654096</ref> <ref>PMID:19496932</ref> [[http://www.uniprot.org/uniprot/CSM2_YEAST CSM2_YEAST]] Involved in chromosome segregation during meiosis. Promotes efficient recombinational repair and functions in the protection of the genome from spontaneous and induced DNA damage like mutations and gross chromosomal rearrangements (GCRs).<ref>PMID:11470404</ref> <ref>PMID:12972632</ref> <ref>PMID:15184655</ref> <ref>PMID:15654096</ref> <ref>PMID:19496932</ref> 
<StructureSection load='3vu9' size='340' side='right'caption='[[3vu9]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[3vu9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VU9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VU9 FirstGlance]. <br>
[[3vu9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VU9 OCA].
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vu9 OCA], [https://pdbe.org/3vu9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vu9 RCSB], [https://www.ebi.ac.uk/pdbsum/3vu9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vu9 ProSAT]</span></td></tr>
<references group="xtra"/><references/>
</table>
[[Category: Saccharomyces cerevisiae s288c]]
== Function ==
[[Category: Hosaka, H.]]
[https://www.uniprot.org/uniprot/PSY3_YEAST PSY3_YEAST] Required for resistance to the DNA-damaging agents methyl methanesulfonate (MMS), cisplatin and oxaliplatin, but not to mitomycin C. Plays a role in protection against mutation accumulation. May be a component of the recombination-repair pathway.<ref>PMID:12149442</ref> <ref>PMID:12482937</ref> <ref>PMID:12972632</ref> <ref>PMID:15173006</ref> <ref>PMID:15654096</ref> <ref>PMID:19496932</ref>  
[[Category: Hunter, N.]]
== References ==
[[Category: Lao, J P.]]
<references/>
[[Category: Nakagawa, A.]]
__TOC__
[[Category: Sanda, E.]]
</StructureSection>
[[Category: Sasanuma, H.]]
[[Category: Large Structures]]
[[Category: Shinohara, A.]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Shinohara, M.]]
[[Category: Hosaka H]]
[[Category: Suzuki, M.]]
[[Category: Hunter N]]
[[Category: Tawaramoto, M.]]
[[Category: Lao JP]]
[[Category: Yamashita, E.]]
[[Category: Nakagawa A]]
[[Category: Dna binding protein]]
[[Category: Sanda E]]
[[Category: Dna repair]]
[[Category: Sasanuma H]]
[[Category: Meiosis]]
[[Category: Shinohara A]]
[[Category: Recombination]]
[[Category: Shinohara M]]
[[Category: Suzuki M]]
[[Category: Tawaramoto M]]
[[Category: Yamashita E]]

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