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==Crystal structure of the tyrosine kinase binding domain of Cbl-c (PL mutant)== | |||
<StructureSection load='3vrq' size='340' side='right'caption='[[3vrq]], [[Resolution|resolution]] 2.39Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3vrq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VRQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VRQ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.39Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vrq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vrq OCA], [https://pdbe.org/3vrq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vrq RCSB], [https://www.ebi.ac.uk/pdbsum/3vrq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vrq ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CBLC_HUMAN CBLC_HUMAN] Regulator of EGFR mediated signal transduction. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Isozaki Y]] | |||
[[Category: Nakagawa A]] | |||
[[Category: Suzuki M]] | |||
[[Category: Takeshita K]] | |||
[[Category: Tezuka T]] | |||
[[Category: Yamamoto T]] | |||
[[Category: Yamanashi Y]] | |||
[[Category: Yamashita E]] | |||
Latest revision as of 11:41, 20 March 2024
Crystal structure of the tyrosine kinase binding domain of Cbl-c (PL mutant)Crystal structure of the tyrosine kinase binding domain of Cbl-c (PL mutant)
Structural highlights
FunctionCBLC_HUMAN Regulator of EGFR mediated signal transduction. |
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