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{{STRUCTURE_3s8r|  PDB=3s8r  |  SCENE=  }}
===Crystal Structures of Glutaryl 7-Aminocephalosporanic Acid Acylase: Insight into Autoproteolytic Activation===
{{ABSTRACT_PUBMED_12680762}}


==Function==
==Crystal Structures of Glutaryl 7-Aminocephalosporanic Acid Acylase: Insight into Autoproteolytic Activation==
[[http://www.uniprot.org/uniprot/G7AC_PSEU7 G7AC_PSEU7]] Catalyzes the deacylation of 7 beta-(4-carboxybutanamido)cephalosporanic acid (glutaryl-7-aminocephalosporanic acid or GL-7-ACA) to 7-aminocephalosporanic acid (7-ACA).<ref>PMID:2993240</ref>
<StructureSection load='3s8r' size='340' side='right'caption='[[3s8r]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[3s8r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._SY-77-1 Pseudomonas sp. SY-77-1]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1oqz 1oqz]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S8R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S8R FirstGlance]. <br>
[[3s8r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas Pseudomonas]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1oqz 1oqz]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S8R OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s8r OCA], [https://pdbe.org/3s8r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s8r RCSB], [https://www.ebi.ac.uk/pdbsum/3s8r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s8r ProSAT]</span></td></tr>
<ref group="xtra">PMID:012680762</ref><references group="xtra"/><references/>
</table>
[[Category: Glutaryl-7-aminocephalosporanic-acid acylase]]
== Function ==
[[Category: Pseudomonas]]
[https://www.uniprot.org/uniprot/G7AC_PSEU7 G7AC_PSEU7] Catalyzes the deacylation of 7 beta-(4-carboxybutanamido)cephalosporanic acid (glutaryl-7-aminocephalosporanic acid or GL-7-ACA) to 7-aminocephalosporanic acid (7-ACA).<ref>PMID:2993240</ref>
[[Category: Kim, J K.]]
== References ==
[[Category: Kim, K H.]]
<references/>
[[Category: Park, S S.]]
__TOC__
[[Category: Yang, I S.]]
</StructureSection>
[[Category: Acylase]]
[[Category: Large Structures]]
[[Category: Hydrolase]]
[[Category: Pseudomonas sp. SY-77-1]]
[[Category: Motif]]
[[Category: Kim JK]]
[[Category: Kim KH]]
[[Category: Park SS]]
[[Category: Yang IS]]

Latest revision as of 11:36, 20 March 2024

Crystal Structures of Glutaryl 7-Aminocephalosporanic Acid Acylase: Insight into Autoproteolytic ActivationCrystal Structures of Glutaryl 7-Aminocephalosporanic Acid Acylase: Insight into Autoproteolytic Activation

Structural highlights

3s8r is a 2 chain structure with sequence from Pseudomonas sp. SY-77-1. This structure supersedes the now removed PDB entry 1oqz. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.5Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

G7AC_PSEU7 Catalyzes the deacylation of 7 beta-(4-carboxybutanamido)cephalosporanic acid (glutaryl-7-aminocephalosporanic acid or GL-7-ACA) to 7-aminocephalosporanic acid (7-ACA).[1]

References

  1. ↑ Matsuda A, Komatsu KI. Molecular cloning and structure of the gene for 7 beta-(4-carboxybutanamido)cephalosporanic acid acylase from a Pseudomonas strain. J Bacteriol. 1985 Sep;163(3):1222-8. PMID:2993240

3s8r, resolution 2.50Å

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OCA
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