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==Structure of CRISPR-associated protein Csn2== | ==Structure of CRISPR-associated protein Csn2== | ||
<StructureSection load='3qhq' size='340' side='right' caption='[[3qhq]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='3qhq' size='340' side='right'caption='[[3qhq]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3qhq]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3qhq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_agalactiae_ATCC_13813 Streptococcus agalactiae ATCC 13813]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QHQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QHQ FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qhq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qhq OCA], [https://pdbe.org/3qhq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qhq RCSB], [https://www.ebi.ac.uk/pdbsum/3qhq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qhq ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/CSN2_STRA8 CSN2_STRA8] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity). Binds dsDNA, binding is disrupted by EGTA. | ||
==See Also== | ==See Also== | ||
*[[Endonuclease|Endonuclease]] | *[[Endonuclease 3D structures|Endonuclease 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Streptococcus agalactiae]] | [[Category: Streptococcus agalactiae ATCC 13813]] | ||
[[Category: Arslan | [[Category: Arslan Z]] | ||
[[Category: Ellinger | [[Category: Ellinger P]] | ||
[[Category: Pfeffer | [[Category: Pfeffer K]] | ||
[[Category: Pul | [[Category: Pul U]] | ||
[[Category: Schmitt | [[Category: Schmitt L]] | ||
[[Category: Smits | [[Category: Smits SH]] | ||
[[Category: Tschapek | [[Category: Tschapek B]] | ||
[[Category: Wagner | [[Category: Wagner R]] | ||
[[Category: Wurm | [[Category: Wurm R]] | ||
Latest revision as of 11:35, 20 March 2024
Structure of CRISPR-associated protein Csn2Structure of CRISPR-associated protein Csn2
Structural highlights
FunctionCSN2_STRA8 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity). Binds dsDNA, binding is disrupted by EGTA. See Also |
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