3kx2: Difference between revisions

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New page: '''Unreleased structure''' The entry 3kx2 is ON HOLD Authors: Nielsen, K.H., Andersen, G.R., He, Y. Description: TBA ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec ...
 
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'''Unreleased structure'''


The entry 3kx2 is ON HOLD
==Crystal structure of Prp43p in complex with ADP==
<StructureSection load='3kx2' size='340' side='right'caption='[[3kx2]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3kx2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KX2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KX2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kx2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kx2 OCA], [https://pdbe.org/3kx2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kx2 RCSB], [https://www.ebi.ac.uk/pdbsum/3kx2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kx2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PRP43_YEAST PRP43_YEAST] Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA.<ref>PMID:9342317</ref> <ref>PMID:16880513</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kx/3kx2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kx2 ConSurf].
<div style="clear:both"></div>


Authors: Nielsen, K.H., Andersen, G.R., He, Y.
==See Also==
 
*[[Helicase 3D structures|Helicase 3D structures]]
Description: TBA
*[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]]
 
== References ==
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec  9 14:45:41 2009''
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Andersen GR]]
[[Category: He Y]]
[[Category: Nielsen KH]]

Latest revision as of 11:30, 20 March 2024

Crystal structure of Prp43p in complex with ADPCrystal structure of Prp43p in complex with ADP

Structural highlights

3kx2 is a 2 chain structure with sequence from Saccharomyces cerevisiae S288C. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PRP43_YEAST Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA.[1] [2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Arenas JE, Abelson JN. Prp43: An RNA helicase-like factor involved in spliceosome disassembly. Proc Natl Acad Sci U S A. 1997 Oct 28;94(22):11798-802. PMID:9342317
  2. ↑ Boon KL, Auchynnikava T, Edwalds-Gilbert G, Barrass JD, Droop AP, Dez C, Beggs JD. Yeast ntr1/spp382 mediates prp43 function in postspliceosomes. Mol Cell Biol. 2006 Aug;26(16):6016-23. PMID:16880513 doi:http://dx.doi.org/10.1128/MCB.02347-05

3kx2, resolution 2.20Å

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