3ebl: Difference between revisions

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[[Image:3ebl.jpg|left|200px]]


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==Crystal Structure of Rice GID1 complexed with GA4==
The line below this paragraph, containing "STRUCTURE_3ebl", creates the "Structure Box" on the page.
<StructureSection load='3ebl' size='340' side='right'caption='[[3ebl]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3ebl]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa_Japonica_Group Oryza sativa Japonica Group]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EBL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EBL FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GA4:GIBBERELLIN+A4'>GA4</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
{{STRUCTURE_3ebl|  PDB=3ebl  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ebl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ebl OCA], [https://pdbe.org/3ebl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ebl RCSB], [https://www.ebi.ac.uk/pdbsum/3ebl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ebl ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of Rice GID1 complexed with GA4===
== Function ==
 
[https://www.uniprot.org/uniprot/GID1_ORYSJ GID1_ORYSJ] Functions as soluble gibberellin (GA) receptor. GA is an essential hormone that regulates growth and development in plants. Binds with high affinity the biologically active GAs such as GA1, GA3 and GA4, but has low or no affinity for the biologically inactive GAs. Upon GA-binding, it interacts with the DELLA protein SLR1, a repressor of GA signaling. This leads to SLR1 degradation by the proteasome, allowing the GA signaling pathway.
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
3EBL is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Oryza_sativa_japonica_group Oryza sativa japonica group]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EBL OCA].  
Check<jmol>
[[Category: Oryza sativa japonica group]]
  <jmolCheckbox>
[[Category: Kato, H.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/3ebl_consurf.spt"</scriptWhenChecked>
[[Category: Matsuoka, M.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Nakatsu, T.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Shimada, A.]]
  </jmolCheckbox>
[[Category: Ueguchi-Tanaka, M.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ebl ConSurf].
[[Category: Alpha/beta hydrolase]]
<div style="clear:both"></div>
[[Category: Gibberellin signaling pathway]]
__TOC__
[[Category: Hydrolase]]
</StructureSection>
[[Category: Hydrolase receptor]]
[[Category: Large Structures]]
[[Category: Lipase]]
[[Category: Oryza sativa Japonica Group]]
[[Category: Nucleus]]
[[Category: Kato H]]
[[Category: Receptor]]
[[Category: Matsuoka M]]
 
[[Category: Nakatsu T]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 27 13:38:25 2008''
[[Category: Shimada A]]
[[Category: Ueguchi-Tanaka M]]

Latest revision as of 11:24, 20 March 2024

Crystal Structure of Rice GID1 complexed with GA4Crystal Structure of Rice GID1 complexed with GA4

Structural highlights

3ebl is a 6 chain structure with sequence from Oryza sativa Japonica Group. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GID1_ORYSJ Functions as soluble gibberellin (GA) receptor. GA is an essential hormone that regulates growth and development in plants. Binds with high affinity the biologically active GAs such as GA1, GA3 and GA4, but has low or no affinity for the biologically inactive GAs. Upon GA-binding, it interacts with the DELLA protein SLR1, a repressor of GA signaling. This leads to SLR1 degradation by the proteasome, allowing the GA signaling pathway.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

3ebl, resolution 1.90Å

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OCA
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