3ebl: Difference between revisions

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-{{STRUCTURE_3ebl|  PDB=3ebl  |  SCENE=  }}
-===Crystal Structure of Rice GID1 complexed with GA4===
-{{ABSTRACT_PUBMED_19037316}}
-==Function==
+==Crystal Structure of Rice GID1 complexed with GA4==
-[[http://www.uniprot.org/uniprot/GID1_ORYSJ GID1_ORYSJ]] Functions as soluble gibberellin (GA) receptor. GA is an essential hormone that regulates growth and development in plants. Binds with high affinity the biologically active GAs such as GA1, GA3 and GA4, but has low or no affinity for the biologically inactive GAs. Upon GA-binding, it interacts with the DELLA protein SLR1, a repressor of GA signaling. This leads to SLR1 degradation by the proteasome, allowing the GA signaling pathway.
+<StructureSection load='3ebl' size='340' side='right'caption='[[3ebl]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
+== Structural highlights ==
-==About this Structure==
+<table><tr><td colspan='2'>[[3ebl]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa_Japonica_Group Oryza sativa Japonica Group]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EBL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EBL FirstGlance]. <br>
-[[3ebl]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Japanese_rice Japanese rice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EBL OCA].
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GA4:GIBBERELLIN+A4'>GA4</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-==Reference==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ebl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ebl OCA], [https://pdbe.org/3ebl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ebl RCSB], [https://www.ebi.ac.uk/pdbsum/3ebl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ebl ProSAT]</span></td></tr>
-<ref group="xtra">PMID:019037316</ref><references group="xtra"/><references/>
+</table>
-[[Category: Japanese rice]]
+== Function ==
-[[Category: Kato, H.]]
+[https://www.uniprot.org/uniprot/GID1_ORYSJ GID1_ORYSJ] Functions as soluble gibberellin (GA) receptor. GA is an essential hormone that regulates growth and development in plants. Binds with high affinity the biologically active GAs such as GA1, GA3 and GA4, but has low or no affinity for the biologically inactive GAs. Upon GA-binding, it interacts with the DELLA protein SLR1, a repressor of GA signaling. This leads to SLR1 degradation by the proteasome, allowing the GA signaling pathway.
-[[Category: Matsuoka, M.]]
+== Evolutionary Conservation ==
-[[Category: Nakatsu, T.]]
+[[Image:Consurf_key_small.gif|200px|right]]
-[[Category: Shimada, A.]]
+Check<jmol>
-[[Category: Ueguchi-Tanaka, M.]]
+  <jmolCheckbox>
-[[Category: Alpha/beta hydrolase]]
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/3ebl_consurf.spt"</scriptWhenChecked>
-[[Category: Gibberellin signaling pathway]]
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-[[Category: Hydrolase]]
+    <text>to colour the structure by Evolutionary Conservation</text>
-[[Category: Hydrolase receptor]]
+  </jmolCheckbox>
-[[Category: Lipase]]
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ebl ConSurf].
-[[Category: Nucleus]]
+<div style="clear:both"></div>
-[[Category: Receptor]]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Oryza sativa Japonica Group]]
+[[Category: Kato H]]
+[[Category: Matsuoka M]]
+[[Category: Nakatsu T]]
+[[Category: Shimada A]]
+[[Category: Ueguchi-Tanaka M]]