3e6u: Difference between revisions

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[[Image:3e6u.jpg|left|200px]]


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==Crystal structure of Human LanCL1==
The line below this paragraph, containing "STRUCTURE_3e6u", creates the "Structure Box" on the page.
<StructureSection load='3e6u' size='340' side='right'caption='[[3e6u]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3e6u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E6U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E6U FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_3e6u|  PDB=3e6u  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e6u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e6u OCA], [https://pdbe.org/3e6u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e6u RCSB], [https://www.ebi.ac.uk/pdbsum/3e6u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e6u ProSAT]</span></td></tr>
 
</table>
===Crystal structure of Human LanCL1===
== Function ==
 
[https://www.uniprot.org/uniprot/LANC1_HUMAN LANC1_HUMAN] May play a role in EPS8 signaling. Binds glutathion.<ref>PMID:19528316</ref>  
 
== Evolutionary Conservation ==
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Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e6/3e6u_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_19528316}}
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
3E6U is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E6U OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3e6u ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
<ref group="xtra">PMID:19528316</ref><references group="xtra"/>
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Li, X.]]
[[Category: Large Structures]]
[[Category: Rao, Z.]]
[[Category: Li X]]
[[Category: Zhang, C.]]
[[Category: Rao Z]]
[[Category: Zhang, W.]]
[[Category: Zhang C]]
[[Category: Zhu, G.]]
[[Category: Zhang W]]
[[Category: Alpha barrel]]
[[Category: Zhu G]]
[[Category: Cytoplasm]]
[[Category: Signaling protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 25 09:09:18 2009''

Latest revision as of 11:24, 20 March 2024

Crystal structure of Human LanCL1Crystal structure of Human LanCL1

Structural highlights

3e6u is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.6Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LANC1_HUMAN May play a role in EPS8 signaling. Binds glutathion.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Zhang W, Wang L, Liu Y, Xu J, Zhu G, Cang H, Li X, Bartlam M, Hensley K, Li G, Rao Z, Zhang XC. Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione. Genes Dev. 2009 Jun 15;23(12):1387-92. PMID:19528316 doi:23/12/1387

3e6u, resolution 2.60Å

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