4frd: Difference between revisions

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'''Unreleased structure'''


The entry 4frd is ON HOLD
==Crystal Structure of ABBA+UDP+Gal at pH 9.0 with MPD as the cryoprotectant==
<StructureSection load='4frd' size='340' side='right'caption='[[4frd]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4frd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FRD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FRD FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4frd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4frd OCA], [https://pdbe.org/4frd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4frd RCSB], [https://www.ebi.ac.uk/pdbsum/4frd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4frd ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.


Authors: Johal, A.R., Alfaro, J.A., Blackler, R.J., Schuman, B., Borisova, S.N., Evans, S.V.
==See Also==
 
*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
Description: Crystal Structure of ABBA+UDP+Gal at pH 9.0 with MPD as the cryoprotectant
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Alfaro JA]]
[[Category: Blackler RJ]]
[[Category: Borisova SN]]
[[Category: Evans SV]]
[[Category: Johal AR]]
[[Category: Schuman B]]

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