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==Crystal Structure of Shikimate Dehydrogenase (aroE) Y210S Mutant from Helicobacter pylori in Complex with Shikimate==
==Crystal Structure of Shikimate Dehydrogenase (aroE) Y210S Mutant from Helicobacter pylori in Complex with Shikimate==
<StructureSection load='4fr5' size='340' side='right' caption='[[4fr5]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='4fr5' size='340' side='right'caption='[[4fr5]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4fr5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FR5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FR5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4fr5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FR5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FR5 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SKM:(3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC+ACID'>SKM</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3phg|3phg]], [[3phh|3phh]], [[3phi|3phi]], [[3phj|3phj]], [[4foo|4foo]], [[4fos|4fos]], [[4fpx|4fpx]], [[4fq8|4fq8]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SKM:(3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC+ACID'>SKM</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aroE, HP_1249 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=85962 Campylobacter pylori])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fr5 OCA], [https://pdbe.org/4fr5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fr5 RCSB], [https://www.ebi.ac.uk/pdbsum/4fr5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fr5 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Shikimate_dehydrogenase Shikimate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.25 1.1.1.25] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fr5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fr5 RCSB], [http://www.ebi.ac.uk/pdbsum/4fr5 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AROE_HELPY AROE_HELPY]


==See Also==
==See Also==
*[[Shikimate dehydrogenase|Shikimate dehydrogenase]]
*[[Shikimate dehydrogenase 3D structures|Shikimate dehydrogenase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Campylobacter pylori]]
[[Category: Helicobacter pylori 26695]]
[[Category: Shikimate dehydrogenase]]
[[Category: Large Structures]]
[[Category: Chen, T J]]
[[Category: Chen TJ]]
[[Category: Cheng, W C]]
[[Category: Cheng WC]]
[[Category: Wang, W C]]
[[Category: Wang WC]]
[[Category: Dehydrogenase]]
[[Category: Nadp binding]]
[[Category: Oxidoreductase]]

Latest revision as of 18:32, 14 March 2024

Crystal Structure of Shikimate Dehydrogenase (aroE) Y210S Mutant from Helicobacter pylori in Complex with ShikimateCrystal Structure of Shikimate Dehydrogenase (aroE) Y210S Mutant from Helicobacter pylori in Complex with Shikimate

Structural highlights

4fr5 is a 2 chain structure with sequence from Helicobacter pylori 26695. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

AROE_HELPY

See Also

4fr5, resolution 2.20Å

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