4fqw: Difference between revisions
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New page: '''Unreleased structure''' The entry 4fqw is ON HOLD Authors: Johal, A.R., Alfaro, J.A., Blackler, R.J., Schuman, B., Borisova, S.N., Evans, S.V. Description: Crystal Structure of AAAA... |
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==Crystal Structure of AAAA+UDP+Gal at pH 5.0 with MPD as the cryoprotectant== | |||
<StructureSection load='4fqw' size='340' side='right'caption='[[4fqw]], [[Resolution|resolution]] 2.02Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4fqw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FQW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FQW FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.02Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fqw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fqw OCA], [https://pdbe.org/4fqw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fqw RCSB], [https://www.ebi.ac.uk/pdbsum/4fqw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fqw ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. | |||
==See Also== | |||
*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Alfaro JA]] | |||
[[Category: Blackler RJ]] | |||
[[Category: Borisova SN]] | |||
[[Category: Evans SV]] | |||
[[Category: Johal AR]] | |||
[[Category: Schuman B]] | |||
Latest revision as of 18:31, 14 March 2024
Crystal Structure of AAAA+UDP+Gal at pH 5.0 with MPD as the cryoprotectantCrystal Structure of AAAA+UDP+Gal at pH 5.0 with MPD as the cryoprotectant
Structural highlights
FunctionBGAT_HUMAN This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. See Also |
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