4foa: Difference between revisions
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New page: '''Unreleased structure''' The entry 4foa is ON HOLD Authors: Reddy, M.C.M., Bruning, J.B., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC) Description: Crystal Structure ... |
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==Crystal Structure of the Mtb ThyA in Complex with 5-fluoro-dUMP== | |||
<StructureSection load='4foa' size='340' side='right'caption='[[4foa]], [[Resolution|resolution]] 2.25Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4foa]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FOA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FOA FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.253Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UFP:5-FLUORO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>UFP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4foa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4foa OCA], [https://pdbe.org/4foa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4foa RCSB], [https://www.ebi.ac.uk/pdbsum/4foa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4foa ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TYSY_MYCTU TYSY_MYCTU] Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity). | |||
==See Also== | |||
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis H37Rv]] | |||
[[Category: Bruning JB]] | |||
[[Category: Reddy MCM]] | |||
[[Category: Sacchettini JC]] | |||
Latest revision as of 18:30, 14 March 2024
Crystal Structure of the Mtb ThyA in Complex with 5-fluoro-dUMPCrystal Structure of the Mtb ThyA in Complex with 5-fluoro-dUMP
Structural highlights
FunctionTYSY_MYCTU Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity). See Also |
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