4fns: Difference between revisions

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'''Unreleased structure'''


The entry 4fns is ON HOLD  until Paper Publication
==Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin==
<StructureSection load='4fns' size='340' side='right'caption='[[4fns]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4fns]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FNS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FNS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DGJ:(2R,3S,4R,5S)-2-(HYDROXYMETHYL)PIPERIDINE-3,4,5-TRIOL'>DGJ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fns OCA], [https://pdbe.org/4fns PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fns RCSB], [https://www.ebi.ac.uk/pdbsum/4fns PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fns ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AGAA_GEOSE AGAA_GEOSE] Hydrolyzes the short-chain alpha-galactosaccharides raffinose and stachyose.<ref>PMID:23012371</ref>


Authors: Merceron, R., Foucault, M., Haser, R., Mattes, R., Watzlawick, H., Gouet, P.
==See Also==
 
*[[Galactosidase 3D structures|Galactosidase 3D structures]]
Description: Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Geobacillus stearothermophilus]]
[[Category: Large Structures]]
[[Category: Foucault M]]
[[Category: Gouet P]]
[[Category: Haser R]]
[[Category: Mattes R]]
[[Category: Merceron R]]
[[Category: Watzlawick H]]

Latest revision as of 18:30, 14 March 2024

Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycinCrystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin

Structural highlights

4fns is a 4 chain structure with sequence from Geobacillus stearothermophilus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.6Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

AGAA_GEOSE Hydrolyzes the short-chain alpha-galactosaccharides raffinose and stachyose.[1]

See Also

References

  1. Merceron R, Foucault M, Haser R, Mattes R, Watzlawick H, Gouet P. The molecular mechanism of thermostable alpha-galactosidases AgaA and AgaB explained by x-ray crystallography and mutational studies. J Biol Chem. 2012 Nov 16;287(47):39642-52. doi: 10.1074/jbc.M112.394114. Epub, 2012 Sep 25. PMID:23012371 doi:http://dx.doi.org/10.1074/jbc.M112.394114

4fns, resolution 2.60Å

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