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==Crystal structure of pyridoxal biosynthesis lyase PdxS from Pyrococcus horikoshii== | |||
<StructureSection load='4fiq' size='340' side='right'caption='[[4fiq]], [[Resolution|resolution]] 2.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4fiq]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FIQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FIQ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fiq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fiq OCA], [https://pdbe.org/4fiq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fiq RCSB], [https://www.ebi.ac.uk/pdbsum/4fiq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fiq ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PDXS_PYRHO PDXS_PYRHO] Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.[HAMAP-Rule:MF_01824] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Pyrococcus horikoshii OT3]] | |||
[[Category: Lee HH]] | |||
[[Category: Matsuura A]] | |||
[[Category: Suh SW]] | |||
[[Category: Yoon HJ]] | |||
[[Category: Yoon JY]] |
Latest revision as of 18:26, 14 March 2024
Crystal structure of pyridoxal biosynthesis lyase PdxS from Pyrococcus horikoshiiCrystal structure of pyridoxal biosynthesis lyase PdxS from Pyrococcus horikoshii
Structural highlights
FunctionPDXS_PYRHO Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.[HAMAP-Rule:MF_01824] |
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