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==Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - MgCTP bound== | |||
<StructureSection load='4fhv' size='340' side='right'caption='[[4fhv]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4fhv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FHV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FHV FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fhv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fhv OCA], [https://pdbe.org/4fhv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fhv RCSB], [https://www.ebi.ac.uk/pdbsum/4fhv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fhv ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CID1_SCHPO CID1_SCHPO] Involved in cell cycle arrest where in association with crb2/rhp9 and chk1 it inhibits unscheduled mitosis. | |||
=== | ==See Also== | ||
*[[Poly(A) RNA polymerase|Poly(A) RNA polymerase]] | |||
__TOC__ | |||
</StructureSection> | |||
[[ | [[Category: Large Structures]] | ||
[[Category: Schizosaccharomyces pombe 972h-]] | [[Category: Schizosaccharomyces pombe 972h-]] | ||
[[Category: Lunde | [[Category: Lunde BM]] | ||
[[Category: Magler | [[Category: Magler I]] | ||
[[Category: Meinhart | [[Category: Meinhart A]] | ||
Latest revision as of 18:25, 14 March 2024
Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - MgCTP boundCrystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - MgCTP bound
Structural highlights
FunctionCID1_SCHPO Involved in cell cycle arrest where in association with crb2/rhp9 and chk1 it inhibits unscheduled mitosis. See Also |
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