4fex: Difference between revisions

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-{{STRUCTURE_4fex|  PDB=4fex  |  SCENE=  }}
-===Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor tyrphostin AG1478===
-{{ABSTRACT_PUBMED_23758273}}
-==About this Structure==
+==Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor tyrphostin AG1478==
-[[4fex]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Acinetobacter_baumannii_aye Acinetobacter baumannii aye]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FEX OCA].
+<StructureSection load='4fex' size='340' side='right'caption='[[4fex]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4fex]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Acinetobacter_baumannii_AYE Acinetobacter baumannii AYE]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FEX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FEX FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.71&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0TO:N-(3-CHLOROPHENYL)-6,7-DIMETHOXYQUINAZOLIN-4-AMINE'>0TO</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=KAN:KANAMYCIN+A'>KAN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fex OCA], [https://pdbe.org/4fex PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fex RCSB], [https://www.ebi.ac.uk/pdbsum/4fex PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fex ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/B0VD92_ACIBY B0VD92_ACIBY]
 ==See Also==
-*[[Phosphotransferase|Phosphotransferase]]
+*[[Phosphotransferase 3D structures|Phosphotransferase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:023758273</ref><references group="xtra"/><references/>
+[[Category: Acinetobacter baumannii AYE]]
-[[Category: Acinetobacter baumannii aye]]
+[[Category: Large Structures]]
-[[Category: Kanamycin kinase]]
+[[Category: Anderson WF]]
-[[Category: Anderson, W F.]]
+[[Category: Di Leo R]]
-[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
+[[Category: Egorova O]]
-[[Category: Egorova, O.]]
+[[Category: Evdokimova E]]
-[[Category: Evdokimova, E.]]
+[[Category: Minasov G]]
-[[Category: Leo, R Di.]]
+[[Category: Savchenko A]]
-[[Category: Minasov, G.]]
+[[Category: Shakya T]]
-[[Category: Savchenko, A.]]
+[[Category: Spanogiannopoulos P]]
-[[Category: Shakya, T.]]
+[[Category: Stogios PJ]]
-[[Category: Spanogiannopoulos, P.]]
+[[Category: Wawrzak Z]]
-[[Category: Stogios, P J.]]
+[[Category: Wright GD]]
-[[Category: Wawrzak, Z.]]
-[[Category: Wright, G D.]]
-[[Category: 4-anilinoquinazoline]]
-[[Category: Ag1478]]
-[[Category: Alpha/beta protein]]
-[[Category: Aminoglycoside phosphotransferase]]
-[[Category: Aminoglycoside]]
-[[Category: Antibiotic resistance]]
-[[Category: Center for structural genomics of infectious disease]]
-[[Category: Csgid]]
-[[Category: Eukaryotic protein kinase-like fold]]
-[[Category: Gtp]]
-[[Category: Intracellular]]
-[[Category: Kanamycin]]
-[[Category: National institute of allergy and infectious disease]]
-[[Category: Niaid]]
-[[Category: Phosphotransferase]]
-[[Category: Protein kinase inhibitor]]
-[[Category: Transferase]]
-[[Category: Transferase-transferase inhibitor complex]]
-[[Category: Tyrphostin]]
-[[Category: Tyrphostin ag1478]]