4fev: Difference between revisions

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OCA

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-'''Unreleased structure'''
-The entry 4fev is ON HOLD
+==Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor pyrazolopyrimidine PP1==
+<StructureSection load='4fev' size='340' side='right'caption='[[4fev]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4fev]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Acinetobacter_baumannii_AYE Acinetobacter baumannii AYE]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FEV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FEV FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=KAN:KANAMYCIN+A'>KAN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PP1:1-TER-BUTYL-3-P-TOLYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE'>PP1</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fev OCA], [https://pdbe.org/4fev PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fev RCSB], [https://www.ebi.ac.uk/pdbsum/4fev PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fev ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/B0VD92_ACIBY B0VD92_ACIBY]
-Authors: Stogios, P.J., Evdokimova, E., Wawrzak, Z., Minasov, G., Egorova, O., Di Leo, R., Shakya, T., Spanogiannopoulos, P., Wright, G.D., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
+==See Also==
+*[[Phosphotransferase 3D structures|Phosphotransferase 3D structures]]
-Description: Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor pyrazolopyrimidine PP1
+__TOC__
+</StructureSection>
+[[Category: Acinetobacter baumannii AYE]]
+[[Category: Large Structures]]
+[[Category: Anderson WF]]
+[[Category: Di Leo R]]
+[[Category: Egorova O]]
+[[Category: Evdokimova E]]
+[[Category: Minasov G]]
+[[Category: Savchenko A]]
+[[Category: Shakya T]]
+[[Category: Spanogiannopoulos P]]
+[[Category: Stogios PJ]]
+[[Category: Wawrzak Z]]
+[[Category: Wright GD]]