4fb8: Difference between revisions

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-'''Unreleased structure'''
-The entry 4fb8 is ON HOLD  until Nov 27 2014
+==Crystal Structure of apo Acyl-CoA Carboxylase==
+<StructureSection load='4fb8' size='340' side='right'caption='[[4fb8]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-Authors: Reddy, M.C.M., Bruning, J.B., Sherekar, M., Valluru, S., Ehrenfeld, H., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4fb8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FB8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FB8 FirstGlance]. <br>
-Description: Crystal Structure of apo Acyl-CoA Carboxylase
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fb8 OCA], [https://pdbe.org/4fb8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fb8 RCSB], [https://www.ebi.ac.uk/pdbsum/4fb8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fb8 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ACCD6_MYCTU ACCD6_MYCTU] Component of a biotin-dependent acyl-CoA carboxylase complex. This subunit transfers the CO2 from carboxybiotin to the CoA ester substrate (PubMed:17114269). When associated with the alpha3 subunit AccA3, is involved in the carboxylation of acetyl-CoA and propionyl-CoA, with a preference for acetyl-CoA (PubMed:17114269).<ref>PMID:17114269</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Mycobacterium tuberculosis]]
+[[Category: Bruning JB]]
+[[Category: Ehrenfeld H]]
+[[Category: Reddy MCM]]
+[[Category: Sacchettini JC]]
+[[Category: Sherekar M]]
+[[Category: Valluru S]]