4fb8: Difference between revisions
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==Crystal Structure of apo Acyl-CoA Carboxylase== | |||
<StructureSection load='4fb8' size='340' side='right'caption='[[4fb8]], [[Resolution|resolution]] 3.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4fb8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FB8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FB8 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fb8 OCA], [https://pdbe.org/4fb8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fb8 RCSB], [https://www.ebi.ac.uk/pdbsum/4fb8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fb8 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ACCD6_MYCTU ACCD6_MYCTU] Component of a biotin-dependent acyl-CoA carboxylase complex. This subunit transfers the CO2 from carboxybiotin to the CoA ester substrate (PubMed:17114269). When associated with the alpha3 subunit AccA3, is involved in the carboxylation of acetyl-CoA and propionyl-CoA, with a preference for acetyl-CoA (PubMed:17114269).<ref>PMID:17114269</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis]] | |||
[[Category: Bruning JB]] | |||
[[Category: Ehrenfeld H]] | |||
[[Category: Reddy MCM]] | |||
[[Category: Sacchettini JC]] | |||
[[Category: Sherekar M]] | |||
[[Category: Valluru S]] | |||
Latest revision as of 18:20, 14 March 2024
Crystal Structure of apo Acyl-CoA CarboxylaseCrystal Structure of apo Acyl-CoA Carboxylase
Structural highlights
FunctionACCD6_MYCTU Component of a biotin-dependent acyl-CoA carboxylase complex. This subunit transfers the CO2 from carboxybiotin to the CoA ester substrate (PubMed:17114269). When associated with the alpha3 subunit AccA3, is involved in the carboxylation of acetyl-CoA and propionyl-CoA, with a preference for acetyl-CoA (PubMed:17114269).[1] References
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