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[[Image:4fb2.jpg|left|200px]]


{{STRUCTURE_4fb2| PDB=4fb2 | SCENE= }}
==Crystal Structure of Substrate-Free P450cin==
<StructureSection load='4fb2' size='340' side='right'caption='[[4fb2]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4fb2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Citrobacter_braakii Citrobacter braakii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FB2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FB2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.37&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fb2 OCA], [https://pdbe.org/4fb2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fb2 RCSB], [https://www.ebi.ac.uk/pdbsum/4fb2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fb2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CINA_CITBR CINA_CITBR] Involved in the degradation of cineol (eucalyptol). Catalyzes the initial hydroxylation of cineole exclusively at the pro-R carbon to give the (S)-6beta-hydroxycineole. Cineole is the natural substrate of CinA.


===Crystal Structure of Substrate-Free P450cin (FoldIt Target)===
==See Also==
 
*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
[[4fb2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Citrobacter_braakii Citrobacter braakii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FB2 OCA].
[[Category: Citrobacter braakii]]
[[Category: Citrobacter braakii]]
[[Category: Li, H.]]
[[Category: Large Structures]]
[[Category: Madrona, Y.]]
[[Category: Li H]]
[[Category: Poulos, T L.]]
[[Category: Madrona Y]]
[[Category: Tripathi, S M.]]
[[Category: Poulos TL]]
[[Category: Cindoxin]]
[[Category: Tripathi SM]]
[[Category: Heme]]
[[Category: Monooxygenase]]
[[Category: Oxidoreductase]]

Latest revision as of 18:20, 14 March 2024

Crystal Structure of Substrate-Free P450cinCrystal Structure of Substrate-Free P450cin

Structural highlights

4fb2 is a 4 chain structure with sequence from Citrobacter braakii. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.37Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CINA_CITBR Involved in the degradation of cineol (eucalyptol). Catalyzes the initial hydroxylation of cineole exclusively at the pro-R carbon to give the (S)-6beta-hydroxycineole. Cineole is the natural substrate of CinA.

See Also

4fb2, resolution 1.37Å

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