4f4r: Difference between revisions
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New page: '''Unreleased structure''' The entry 4f4r is ON HOLD Authors: Vetting, M.W., Toro, R., Bhosle, R., Al Obaidi, N.F., Morisco, L.L., Wasserman, S.R., Sojitra, S., Washington, E., Scott Gl... |
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==Crystal structure of D-mannonate dehydratase homolog from Chromohalobacter salexigens (Target EFI-502114), with bound NA, ordered loop== | |||
<StructureSection load='4f4r' size='340' side='right'caption='[[4f4r]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4f4r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chromohalobacter_salexigens_DSM_3043 Chromohalobacter salexigens DSM 3043]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F4R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F4R FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f4r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f4r OCA], [https://pdbe.org/4f4r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f4r RCSB], [https://www.ebi.ac.uk/pdbsum/4f4r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f4r ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DMGD_CHRSD DMGD_CHRSD] Has low dehydratase activity with D-mannonate and D-gluconate, suggesting that these are not physiological substrates and that it has no significant role in the in vivo degradation of these compounds. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Chromohalobacter salexigens DSM 3043]] | |||
[[Category: Large Structures]] | |||
[[Category: Al Obaidi NF]] | |||
[[Category: Almo SC]] | |||
[[Category: Bhosle R]] | |||
[[Category: Chowdhury S]] | |||
[[Category: Evans B]] | |||
[[Category: Gerlt JA]] | |||
[[Category: Hammonds J]] | |||
[[Category: Hillerich B]] | |||
[[Category: Imker HJ]] | |||
[[Category: Love J]] | |||
[[Category: Morisco LL]] | |||
[[Category: Scott Glenn A]] | |||
[[Category: Seidel RD]] | |||
[[Category: Sojitra S]] | |||
[[Category: Toro R]] | |||
[[Category: Vetting MW]] | |||
[[Category: Washington E]] | |||
[[Category: Wasserman SR]] | |||
Latest revision as of 18:16, 14 March 2024
Crystal structure of D-mannonate dehydratase homolog from Chromohalobacter salexigens (Target EFI-502114), with bound NA, ordered loopCrystal structure of D-mannonate dehydratase homolog from Chromohalobacter salexigens (Target EFI-502114), with bound NA, ordered loop
Structural highlights
FunctionDMGD_CHRSD Has low dehydratase activity with D-mannonate and D-gluconate, suggesting that these are not physiological substrates and that it has no significant role in the in vivo degradation of these compounds. Has no detectable activity with a panel of 70 other acid sugars (in vitro).[1] References
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