4en0: Difference between revisions

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-[[Image:4en0.jpg|left|200px]]
-<!--
+==Crystal structure of light==
-The line below this paragraph, containing "STRUCTURE_4en0", creates the "Structure Box" on the page.
+<StructureSection load='4en0' size='340' side='right'caption='[[4en0]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[4en0]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3ugn 3ugn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EN0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EN0 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.59&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-{{STRUCTURE_4en0|  PDB=4en0  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4en0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4en0 OCA], [https://pdbe.org/4en0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4en0 RCSB], [https://www.ebi.ac.uk/pdbsum/4en0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4en0 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TNF14_HUMAN TNF14_HUMAN] Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
-===Crystal structure of light===
+==See Also==
+*[[Tumor necrosis factor ligand superfamily 3D structures|Tumor necrosis factor ligand superfamily 3D structures]]
+*[[Tumor necrosis factor receptor 3D structures|Tumor necrosis factor receptor 3D structures]]
-==About this Structure==
+__TOC__
-[[4en0]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3ugn 3ugn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EN0 OCA].
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Almo, S C.]]
+[[Category: Large Structures]]
-[[Category: Bonanno, J B.]]
+[[Category: Almo SC]]
-[[Category: IFN, Atoms-to-Animals:.The Immune Function Network.]]
+[[Category: Bonanno JB]]
-[[Category: Liu, W.]]
+[[Category: Liu W]]
-[[Category: NYSGRC, New York Structural Genomics Research Consortium.]]
+[[Category: Nathenson SG]]
-[[Category: Nathenson, S G.]]
+[[Category: Patskovsky Y]]
-[[Category: Patskovsky, Y.]]
+[[Category: Ramagopal UA]]
-[[Category: Ramagopal, U A.]]
+[[Category: Zhan C]]
-[[Category: Zhan, C.]]
-[[Category: Atoms-to-animals: the immune function network]]
-[[Category: Bind tnf receptor hvem and ltbr]]
-[[Category: Cytokine]]
-[[Category: Dcr3]]
-[[Category: Hvem]]
-[[Category: Ifn]]
-[[Category: Immunity]]
-[[Category: Jelly-roll fold]]
-[[Category: Ltbr]]
-[[Category: Membrane]]
-[[Category: N-glycosylation]]
-[[Category: New york structural genomics research consortium]]
-[[Category: Nysgrc]]
-[[Category: Psi-biology]]
-[[Category: Secreted protein]]
-[[Category: Structural genomic]]
-[[Category: Tnf superfamily]]