4e82: Difference between revisions

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-'''Unreleased structure'''
-The entry 4e82 is ON HOLD  until Paper Publication
+==Crystal structure of monomeric variant of human alpha-defensin 5, HD5 (Glu21EMe mutant)==
+<StructureSection load='4e82' size='340' side='right'caption='[[4e82]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4e82]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E82 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E82 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EME:N-METHYL-L-GLUTAMIC+ACID'>EME</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e82 OCA], [https://pdbe.org/4e82 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e82 RCSB], [https://www.ebi.ac.uk/pdbsum/4e82 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e82 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DEF5_HUMAN DEF5_HUMAN] Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing.<ref>PMID:12021776</ref> <ref>PMID:15616305</ref> <ref>PMID:17088326</ref>
-Authors: Pazgier, M.
+==See Also==
+*[[Defensin 3D structures|Defensin 3D structures]]
-Description: Crystal structure of monomeric variant of human alpha-defensin 5, HD5 (Glu21EMe mutant)
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Pazgier M]]