4e17: Difference between revisions

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-[[Image:4e17.png|left|200px]]
-{{STRUCTURE_4e17|  PDB=4e17  |  SCENE=  }}
+==Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin==
+<StructureSection load='4e17' size='340' side='right'caption='[[4e17]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-===Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4e17]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E17 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E17 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.304&#8491;</td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e17 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e17 OCA], [https://pdbe.org/4e17 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e17 RCSB], [https://www.ebi.ac.uk/pdbsum/4e17 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e17 ProSAT]</span></td></tr>
-[[4e17]] is a 2 chain structure of [[Vinculin]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E17 OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/VINC_CHICK VINC_CHICK] Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.<ref>PMID:15229287</ref> <ref>PMID:20584916</ref> <ref>PMID:20086044</ref>
 ==See Also==
+*[[Catenin 3D structures|Catenin 3D structures]]
 *[[Vinculin|Vinculin]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Gallus gallus]]
+[[Category: Large Structures]]
 [[Category: Mus musculus]]
-[[Category: Bankston, L A.]]
+[[Category: Bankston LA]]
-[[Category: Cadwell, G W.]]
+[[Category: Cadwell GW]]
-[[Category: Choi, H J.]]
+[[Category: Choi H-J]]
-[[Category: Liddington, R C.]]
+[[Category: Liddington RC]]
-[[Category: Pokutta, S.]]
+[[Category: Pokutta S]]
-[[Category: Weis, W I.]]
+[[Category: Weis WI]]
-[[Category: Cell adhesion]]
-[[Category: Four helix bundle]]