4drp: Difference between revisions

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-[[Image:4drp.png|left|200px]]
-<!--
+==Evaluation of Synthetic FK506 Analogs as Ligands for the FK506-Binding Proteins 51 and 52: Complex of FKBP51 with 2-(3-((R)-3-(3,4-dimethoxyphenyl)-1-((S)-1-(2-((1R,2S)-2-ethyl-1-hydroxy-cyclohexyl)-2-oxoacetyl)piperidine-2-carbonyloxy)propyl)phenoxy)acetic acid from cocrystallization==
-The line below this paragraph, containing "STRUCTURE_4drp", creates the "Structure Box" on the page.
+<StructureSection load='4drp' size='340' side='right'caption='[[4drp]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[4drp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DRP FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0MD:{3-[(1R)-3-(3,4-DIMETHOXYPHENYL)-1-({[(2S)-1-{[(1R,2S)-2-ETHYL-1-HYDROXYCYCLOHEXYL](OXO)ACETYL}PIPERIDIN-2-YL]CARBONYL}OXY)PROPYL]PHENOXY}ACETIC+ACID'>0MD</scene></td></tr>
-{{STRUCTURE_4drp|  PDB=4drp  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4drp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4drp OCA], [https://pdbe.org/4drp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4drp RCSB], [https://www.ebi.ac.uk/pdbsum/4drp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4drp ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/FKBP5_HUMAN FKBP5_HUMAN] Interacts with functionally mature heterooligomeric progesterone receptor complexes along with HSP90 and TEBP.
-===Evaluation of Synthetic FK506 Analogs as Ligands for the FK506-Binding Proteins 51 and 52: Complex of FKBP51 with 2-(3-((R)-3-(3,4-dimethoxyphenyl)-1-((S)-1-(2-((1R,2S)-2-ethyl-1-hydroxy-cyclohexyl)-2-oxoacetyl)piperidine-2-carbonyloxy)propyl)phenoxy)acetic acid from cocrystallization===
+==See Also==
+*[[FKBP 3D structures|FKBP 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_22455444}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 22455444 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_22455444}}
-==About this Structure==
-[[4drp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRP OCA].
-==Reference==
-<ref group="xtra">PMID:022455444</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Peptidylprolyl isomerase]]
+[[Category: Large Structures]]
-[[Category: Bracher, A.]]
+[[Category: Bracher A]]
-[[Category: Gaali, S.]]
+[[Category: Gaali S]]
-[[Category: Gopalakrishnan, R.]]
+[[Category: Gopalakrishnan R]]
-[[Category: Hausch, F.]]
+[[Category: Hausch F]]
-[[Category: Hoogeland, B.]]
+[[Category: Hoogeland B]]
-[[Category: Kozany, C.]]
+[[Category: Kozany C]]
-[[Category: Kress, C.]]
+[[Category: Kress C]]
-[[Category: Fk-506 binding domain]]
-[[Category: Hsp90 cochaperone]]
-[[Category: Immunophilin]]
-[[Category: Isomerase]]
-[[Category: Peptidyl-prolyl isomerase]]