4crx: Difference between revisions

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[[Image:4crx.png|left|200px]]


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==ASYMMETRIC DNA-BENDING IN THE CRE-LOXP SITE-SPECIFIC RECOMBINATION SYNAPSE==
The line below this paragraph, containing "STRUCTURE_4crx", creates the "Structure Box" on the page.
<StructureSection load='4crx' size='340' side='right'caption='[[4crx]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[4crx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_P1 Escherichia virus P1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CRX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CRX FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4crx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4crx OCA], [https://pdbe.org/4crx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4crx RCSB], [https://www.ebi.ac.uk/pdbsum/4crx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4crx ProSAT]</span></td></tr>
{{STRUCTURE_4crx| PDB=4crx |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/RECR_BPP1 RECR_BPP1] Catalyzes site-specific recombination between two 34-base-pair LOXP sites. Its role is to maintain the phage genome as a monomeric unit-copy plasmid in the lysogenic state.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cr/4crx_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=4crx ConSurf].
<div style="clear:both"></div>


===ASYMMETRIC DNA-BENDING IN THE CRE-LOXP SITE-SPECIFIC RECOMBINATION SYNAPSE===
==See Also==
 
*[[Resolvase 3D structures|Resolvase 3D structures]]
 
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_10377382}}, adds the Publication Abstract to the page
[[Category: Escherichia virus P1]]
(as it appears on PubMed at http://www.pubmed.gov), where 10377382 is the PubMed ID number.
[[Category: Large Structures]]
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[[Category: Gopaul DN]]
{{ABSTRACT_PUBMED_10377382}}
[[Category: Guo F]]
 
[[Category: Van Duyne GD]]
==About this Structure==
4CRX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_p1 Enterobacteria phage p1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CRX OCA].
 
==Reference==
Asymmetric DNA bending in the Cre-loxP site-specific recombination synapse., Guo F, Gopaul DN, Van Duyne GD, Proc Natl Acad Sci U S A. 1999 Jun 22;96(13):7143-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10377382 10377382]
[[Category: Enterobacteria phage p1]]
[[Category: Single protein]]
[[Category: Duyne, G D.Van.]]
[[Category: Gopaul, D N.]]
[[Category: Guo, F.]]
[[Category: Cre recombinase]]
[[Category: Dna bending]]
[[Category: Protein-dna interaction]]
[[Category: Recombination]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul  3 13:33:29 2008''

Latest revision as of 17:28, 14 March 2024

ASYMMETRIC DNA-BENDING IN THE CRE-LOXP SITE-SPECIFIC RECOMBINATION SYNAPSEASYMMETRIC DNA-BENDING IN THE CRE-LOXP SITE-SPECIFIC RECOMBINATION SYNAPSE

Structural highlights

4crx is a 4 chain structure with sequence from Escherichia virus P1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RECR_BPP1 Catalyzes site-specific recombination between two 34-base-pair LOXP sites. Its role is to maintain the phage genome as a monomeric unit-copy plasmid in the lysogenic state.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

4crx, resolution 2.20Å

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