3tw9: Difference between revisions

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[[Image:3tw9.png|left|200px]]


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==Crystal structure of gluconate dehydratase (TARGET EFI-501679) from Salmonella enterica subsp. enterica serovar Enteritidis str. P125109==
The line below this paragraph, containing "STRUCTURE_3tw9", creates the "Structure Box" on the page.
<StructureSection load='3tw9' size='340' side='right'caption='[[3tw9]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3tw9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Enteritidis_str._P125109 Salmonella enterica subsp. enterica serovar Enteritidis str. P125109]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TW9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TW9 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
{{STRUCTURE_3tw9|  PDB=3tw9  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tw9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tw9 OCA], [https://pdbe.org/3tw9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tw9 RCSB], [https://www.ebi.ac.uk/pdbsum/3tw9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tw9 ProSAT]</span></td></tr>
 
</table>
===Crystal structure of gluconate dehydratase (TARGET EFI-501679) from Salmonella enterica subsp. enterica serovar Enteritidis str. P125109===
== Function ==
 
[https://www.uniprot.org/uniprot/DGD_SALEP DGD_SALEP] Has low D-gluconate dehydratase activity (in vitro), suggesting that it has no significant role in D-gluconate degradation in vivo. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref>
 
== References ==
==About this Structure==
<references/>
[[3tw9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_enteritidis Salmonella enterica subsp. enterica serovar enteritidis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TW9 OCA].  
__TOC__
[[Category: Salmonella enterica subsp. enterica serovar enteritidis]]
</StructureSection>
[[Category: Almo, S C.]]
[[Category: Large Structures]]
[[Category: Bhosle, R.]]
[[Category: Salmonella enterica subsp. enterica serovar Enteritidis str. P125109]]
[[Category: Chowdhury, S.]]
[[Category: Almo SC]]
[[Category: EFI, Enzyme Function Initiative.]]
[[Category: Bhosle R]]
[[Category: Evans, B.]]
[[Category: Chowdhury S]]
[[Category: Gerlt, J A.]]
[[Category: Evans B]]
[[Category: Glenn, A Scott.]]
[[Category: Gerlt JA]]
[[Category: Hammonds, J.]]
[[Category: Hammonds J]]
[[Category: Hillerich, B.]]
[[Category: Hillerich B]]
[[Category: Imker, H J.]]
[[Category: Imker HJ]]
[[Category: Patskovsky, Y.]]
[[Category: Patskovsky Y]]
[[Category: Seidel, R D.]]
[[Category: Scott Glenn A]]
[[Category: Toro, R.]]
[[Category: Seidel RD]]
[[Category: Washington, E.]]
[[Category: Toro R]]
[[Category: Zencheck, W D.]]
[[Category: Washington E]]
[[Category: Enolase]]
[[Category: Zencheck WD]]
[[Category: Lyase]]
[[Category: Magnesium binding site]]

Latest revision as of 16:41, 14 March 2024

Crystal structure of gluconate dehydratase (TARGET EFI-501679) from Salmonella enterica subsp. enterica serovar Enteritidis str. P125109Crystal structure of gluconate dehydratase (TARGET EFI-501679) from Salmonella enterica subsp. enterica serovar Enteritidis str. P125109

Structural highlights

3tw9 is a 4 chain structure with sequence from Salmonella enterica subsp. enterica serovar Enteritidis str. P125109. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.7Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DGD_SALEP Has low D-gluconate dehydratase activity (in vitro), suggesting that it has no significant role in D-gluconate degradation in vivo. Has no detectable activity with a panel of 70 other acid sugars (in vitro).[1]

References

  1. ↑ Wichelecki DJ, Balthazor BM, Chau AC, Vetting MW, Fedorov AA, Fedorov EV, Lukk T, Patskovsky YV, Stead MB, Hillerich BS, Seidel RD, Almo SC, Gerlt JA. Discovery of function in the enolase superfamily: D-mannonate and d-gluconate dehydratases in the D-mannonate dehydratase subgroup. Biochemistry. 2014 Apr 29;53(16):2722-31. doi: 10.1021/bi500264p. Epub 2014 Apr, 15. PMID:24697546 doi:http://dx.doi.org/10.1021/bi500264p

3tw9, resolution 1.70Å

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