3tw9: Difference between revisions
New page: '''Unreleased structure''' The entry 3tw9 is ON HOLD Authors: Patskovsky, Y., Toro, R., Bhosle, R., Hillerich, B., Seidel, R.D., Washington, E., Scott Glen, A., Chowhurdy, S., Evans, B.... |
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==Crystal structure of gluconate dehydratase (TARGET EFI-501679) from Salmonella enterica subsp. enterica serovar Enteritidis str. P125109== | |||
<StructureSection load='3tw9' size='340' side='right'caption='[[3tw9]], [[Resolution|resolution]] 1.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3tw9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Enteritidis_str._P125109 Salmonella enterica subsp. enterica serovar Enteritidis str. P125109]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TW9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TW9 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tw9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tw9 OCA], [https://pdbe.org/3tw9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tw9 RCSB], [https://www.ebi.ac.uk/pdbsum/3tw9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tw9 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DGD_SALEP DGD_SALEP] Has low D-gluconate dehydratase activity (in vitro), suggesting that it has no significant role in D-gluconate degradation in vivo. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Salmonella enterica subsp. enterica serovar Enteritidis str. P125109]] | |||
[[Category: Almo SC]] | |||
[[Category: Bhosle R]] | |||
[[Category: Chowdhury S]] | |||
[[Category: Evans B]] | |||
[[Category: Gerlt JA]] | |||
[[Category: Hammonds J]] | |||
[[Category: Hillerich B]] | |||
[[Category: Imker HJ]] | |||
[[Category: Patskovsky Y]] | |||
[[Category: Scott Glenn A]] | |||
[[Category: Seidel RD]] | |||
[[Category: Toro R]] | |||
[[Category: Washington E]] | |||
[[Category: Zencheck WD]] |