3th8: Difference between revisions
Jump to navigation
Jump to search
New page: '''Unreleased structure''' The entry 3th8 is ON HOLD Authors: Cao, R., Zhu, W., Zhang, Y., Oldfield, E. Description: Structure of E. coli undecaprenyl diphosphate synthase complexed wi... |
No edit summary |
||
| (8 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Structure of E. coli undecaprenyl diphosphate synthase complexed with BPH-1063== | |||
<StructureSection load='3th8' size='340' side='right'caption='[[3th8]], [[Resolution|resolution]] 2.11Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3th8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TH8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TH8 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.114Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TH9:(2Z)-4-({3-[3-(HEXYLOXY)PHENYL]PROPYL}AMINO)-2-HYDROXY-4-OXOBUT-2-ENOIC+ACID'>TH9</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3th8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3th8 OCA], [https://pdbe.org/3th8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3th8 RCSB], [https://www.ebi.ac.uk/pdbsum/3th8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3th8 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/UPPS_ECOLI UPPS_ECOLI] Generates ditrans,octacis-undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP) and farnesyl diphosphate (FPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.<ref>PMID:12756244</ref> | |||
==See Also== | |||
*[[Undecaprenyl pyrophosphate synthase 3D structures|Undecaprenyl pyrophosphate synthase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli K-12]] | |||
[[Category: Large Structures]] | |||
[[Category: Cao R]] | |||
[[Category: Oldfield E]] | |||
[[Category: Zhang Y]] | |||
[[Category: Zhu W]] | |||
Latest revision as of 16:28, 14 March 2024
Structure of E. coli undecaprenyl diphosphate synthase complexed with BPH-1063Structure of E. coli undecaprenyl diphosphate synthase complexed with BPH-1063
Structural highlights
FunctionUPPS_ECOLI Generates ditrans,octacis-undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP) and farnesyl diphosphate (FPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.[1] See AlsoReferences
|
| ||||||||||||||||||