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==Crystal structure of chlorocatechol 1,2-dioxygenase from Pseudomonas putida==
==Crystal structure of chlorocatechol 1,2-dioxygenase from Pseudomonas putida==
<StructureSection load='3th1' size='340' side='right' caption='[[3th1]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
<StructureSection load='3th1' size='340' side='right'caption='[[3th1]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3th1]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_fluorescens_putidus"_flugge_1886 "bacillus fluorescens putidus" flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TH1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TH1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3th1]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TH1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TH1 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3PH:1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE'>3PH</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DTD:DITHIANE+DIOL'>DTD</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.4&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">clcA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 "Bacillus fluorescens putidus" Flugge 1886])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PH:1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE'>3PH</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DTD:DITHIANE+DIOL'>DTD</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3th1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3th1 OCA], [http://pdbe.org/3th1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3th1 RCSB], [http://www.ebi.ac.uk/pdbsum/3th1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3th1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3th1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3th1 OCA], [https://pdbe.org/3th1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3th1 RCSB], [https://www.ebi.ac.uk/pdbsum/3th1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3th1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CLCA_PSEPU CLCA_PSEPU]] Preferentially converts 3-chlorocatechol and 3,5-dichlorocatechol as opposed to other chlorinated catechols. Retains diminished activity toward non-chlorinated substrates.  
[https://www.uniprot.org/uniprot/CLCA_PSEPU CLCA_PSEPU] Preferentially converts 3-chlorocatechol and 3,5-dichlorocatechol as opposed to other chlorinated catechols. Retains diminished activity toward non-chlorinated substrates.


==See Also==
==See Also==
*[[Dioxygenase|Dioxygenase]]
*[[Dioxygenase 3D structures|Dioxygenase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus fluorescens putidus flugge 1886]]
[[Category: Large Structures]]
[[Category: Nonato, M C]]
[[Category: Pseudomonas putida]]
[[Category: Rustiguel, J K]]
[[Category: Nonato MC]]
[[Category: 2-dioxygenase family]]
[[Category: Rustiguel JK]]
[[Category: Catechol 1]]
[[Category: Iron binding]]
[[Category: Oxidoreductase]]

Latest revision as of 16:28, 14 March 2024

Crystal structure of chlorocatechol 1,2-dioxygenase from Pseudomonas putidaCrystal structure of chlorocatechol 1,2-dioxygenase from Pseudomonas putida

Structural highlights

3th1 is a 3 chain structure with sequence from Pseudomonas putida. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.4Å
Ligands:, , , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CLCA_PSEPU Preferentially converts 3-chlorocatechol and 3,5-dichlorocatechol as opposed to other chlorinated catechols. Retains diminished activity toward non-chlorinated substrates.

See Also

3th1, resolution 3.40Å

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