3srx: Difference between revisions
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==New Delhi Metallo-beta-Lactamase-1 Complexed with Cd== | |||
<StructureSection load='3srx' size='340' side='right'caption='[[3srx]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3srx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SRX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SRX FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |||
== | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr> | ||
[[3srx]] is a 2 chain structure with sequence from [ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3srx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3srx OCA], [https://pdbe.org/3srx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3srx RCSB], [https://www.ebi.ac.uk/pdbsum/3srx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3srx ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin. | |||
==See Also== | ==See Also== | ||
*[[Beta-lactamase|Beta-lactamase]] | *[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Klebsiella pneumoniae]] | [[Category: Klebsiella pneumoniae]] | ||
[[Category: Babnigg | [[Category: Large Structures]] | ||
[[Category: Binkowski | [[Category: Babnigg J]] | ||
[[Category: Jedrzejczak | [[Category: Binkowski TA]] | ||
[[Category: Joachimiak | [[Category: Jedrzejczak R]] | ||
[[Category: Kim | [[Category: Joachimiak A]] | ||
[[Category: Kim Y]] | |||
[[Category: Mire J]] | |||
[[Category: Mire | [[Category: Sacchettini J]] | ||
[[Category: Sacchettini | [[Category: Tesar C]] | ||
[[Category: Tesar | |||
Latest revision as of 16:05, 14 March 2024
New Delhi Metallo-beta-Lactamase-1 Complexed with CdNew Delhi Metallo-beta-Lactamase-1 Complexed with Cd
Structural highlights
FunctionBLAN1_KLEPN Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin. See Also |
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