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==Human Pantothenate kinase 3 in complex with a pantothenate analog==
==Human Pantothenate kinase 3 in complex with a pantothenate analog==
<StructureSection load='3sms' size='340' side='right' caption='[[3sms]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='3sms' size='340' side='right'caption='[[3sms]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3sms]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SMS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SMS FirstGlance]. <br>
<table><tr><td colspan='2'>[[3sms]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SMS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SMS FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=RNH:(2R)-N-[3-(HEPTYLAMINO)-3-OXOPROPYL]-2,4-DIHYDROXY-3,3-DIMETHYLBUTANAMIDE'>RNH</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PANK3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=RNH:(2R)-N-[3-(HEPTYLAMINO)-3-OXOPROPYL]-2,4-DIHYDROXY-3,3-DIMETHYLBUTANAMIDE'>RNH</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantothenate_kinase Pantothenate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.33 2.7.1.33] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sms OCA], [https://pdbe.org/3sms PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sms RCSB], [https://www.ebi.ac.uk/pdbsum/3sms PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sms ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sms OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sms RCSB], [http://www.ebi.ac.uk/pdbsum/3sms PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/PANK3_HUMAN PANK3_HUMAN] Plays a role in the physiological regulation of the intracellular CoA concentration (By similarity).


==See Also==
==See Also==
*[[Pantothenate kinase|Pantothenate kinase]]
*[[Pantothenate kinase 3D structures|Pantothenate kinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Pantothenate kinase]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith CH]]
[[Category: Bolshan, Y.]]
[[Category: Bolshan Y]]
[[Category: Bountra, C.]]
[[Category: Bountra C]]
[[Category: Edwards, A M.]]
[[Category: Edwards AM]]
[[Category: Hong, B.]]
[[Category: Hong B]]
[[Category: Mottaghi, K.]]
[[Category: Mottaghi K]]
[[Category: Park, H.]]
[[Category: Park H]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Smil D]]
[[Category: Smil, D.]]
[[Category: Tempel W]]
[[Category: Tempel, W.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Wernimont AK]]
[[Category: Wernimont, A K.]]
[[Category: Sgc]]
[[Category: Structural genomics consortium]]
[[Category: Transferase]]

Latest revision as of 16:01, 14 March 2024

Human Pantothenate kinase 3 in complex with a pantothenate analogHuman Pantothenate kinase 3 in complex with a pantothenate analog

Structural highlights

3sms is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PANK3_HUMAN Plays a role in the physiological regulation of the intracellular CoA concentration (By similarity).

See Also

3sms, resolution 2.20Å

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