3sm9: Difference between revisions

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-[[Image:3sm9.png|left|200px]]
-{{STRUCTURE_3sm9|  PDB=3sm9  |  SCENE=  }}
+==Crystal Structure of Metabotropic glutamate receptor 3 precursor in presence of LY341495 antagonist==
+<StructureSection load='3sm9' size='340' side='right'caption='[[3sm9]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
-===Crystal Structure of Metabotropic glutamate receptor 3 precursor in presence of LY341495 antagonist===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3sm9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SM9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SM9 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.26&#8491;</td></tr>
-==About this Structure==
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=Z99:2-[(1S,2S)-2-CARBOXYCYCLOPROPYL]-3-(9H-XANTHEN-9-YL)-D-ALANINE'>Z99</scene></td></tr>
-[[3sm9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SM9 OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sm9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sm9 OCA], [https://pdbe.org/3sm9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sm9 RCSB], [https://www.ebi.ac.uk/pdbsum/3sm9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sm9 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/GRM3_HUMAN GRM3_HUMAN] G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.<ref>PMID:8840013</ref>
 ==See Also==
-*[[Ionotropic Glutamate Receptors|Ionotropic Glutamate Receptors]]
+*[[Metabotropic glutamate receptor 3D structures|Metabotropic glutamate receptor 3D structures]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Arrowsmith, C H.]]
+[[Category: Large Structures]]
-[[Category: Bountra, C.]]
+[[Category: Arrowsmith CH]]
-[[Category: Cossar, D.]]
+[[Category: Bountra C]]
-[[Category: Crombet, L.]]
+[[Category: Cossar D]]
-[[Category: Dobrovetsky, E.]]
+[[Category: Crombet L]]
-[[Category: Dong, A.]]
+[[Category: Dobrovetsky E]]
-[[Category: Edwards, A M.]]
+[[Category: Dong A]]
-[[Category: Khutoreskaya, G.]]
+[[Category: Edwards AM]]
-[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Khutoreskaya G]]
-[[Category: Seitova, A.]]
+[[Category: Seitova A]]
-[[Category: Weigelt, J.]]
+[[Category: Weigelt J]]
-[[Category: Wernimont, A K.]]
+[[Category: Wernimont AK]]
-[[Category: Cell membrane]]
-[[Category: G-protein coupled receptor]]
-[[Category: Glycoprotein]]
-[[Category: Membrane]]
-[[Category: Olfaction]]
-[[Category: Phosphoprotein]]
-[[Category: Receptor]]
-[[Category: Sensory transduction]]
-[[Category: Sgc]]
-[[Category: Signaling protein]]
-[[Category: Structural genomic]]
-[[Category: Structural genomics consortium]]
-[[Category: Transducer]]
-[[Category: Transmembrane]]
-[[Category: Transmembrane helix]]