3sjq: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(4 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:3sjq.jpg|left|200px]]


<!--
==Crystal structure of a small conductance potassium channel splice variant complexed with calcium-calmodulin==
The line below this paragraph, containing "STRUCTURE_3sjq", creates the "Structure Box" on the page.
<StructureSection load='3sjq' size='340' side='right'caption='[[3sjq]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3sjq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SJQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SJQ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PHU:1-PHENYLUREA'>PHU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_3sjq|  PDB=3sjq  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sjq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sjq OCA], [https://pdbe.org/3sjq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sjq RCSB], [https://www.ebi.ac.uk/pdbsum/3sjq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sjq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CALM1_RAT CALM1_RAT] Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Mediates calcium-dependent inactivation of CACNA1C. Positively regulates calcium-activated potassium channel activity of KCNN2.[UniProtKB:P62158]


===Crystal structure of a small conductance potassium channel splice variant complexed with calcium-calmodulin===
==See Also==
 
*[[Calmodulin 3D structures|Calmodulin 3D structures]]
 
*[[Potassium channel 3D structures|Potassium channel 3D structures]]
<!--
__TOC__
The line below this paragraph, {{ABSTRACT_PUBMED_22579256}}, adds the Publication Abstract to the page
</StructureSection>
(as it appears on PubMed at http://www.pubmed.gov), where 22579256 is the PubMed ID number.
[[Category: Large Structures]]
-->
{{ABSTRACT_PUBMED_22579256}}
 
==About this Structure==
[[3sjq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SJQ OCA].
 
==Reference==
<ref group="xtra">PMID:022579256</ref><references group="xtra"/>
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Pascal, J M.]]
[[Category: Pascal JM]]
[[Category: Zhang, J F.]]
[[Category: Zhang J-F]]
[[Category: Zhang, M.]]
[[Category: Zhang M]]
[[Category: Calcium binding]]
[[Category: Calmodulin]]
[[Category: Ef hand]]
[[Category: Metal binding protein]]
[[Category: Protein-protein complex]]

Latest revision as of 15:59, 14 March 2024

Crystal structure of a small conductance potassium channel splice variant complexed with calcium-calmodulinCrystal structure of a small conductance potassium channel splice variant complexed with calcium-calmodulin

Structural highlights

3sjq is a 4 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CALM1_RAT Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Mediates calcium-dependent inactivation of CACNA1C. Positively regulates calcium-activated potassium channel activity of KCNN2.[UniProtKB:P62158]

See Also

3sjq, resolution 1.90Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=3sjq&oldid=4097464"